T26A (p.Thr26Ala) variant of TLR3 (Toll-like receptor 3)
T26A (p.Thr26Ala) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
T26A (p.Thr26Ala) variant details
- p.Thr26Ala
- gnomAD 4-186076695-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.08
- MetaLR 0.03
- MetaSVM -1.03
- CADD 14.20
- PolyPhen-2 0.03
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available