T25S (p.Thr25Ser) variant of TLR3 (Toll-like receptor 3)
T25S (p.Thr25Ser) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
T25S (p.Thr25Ser) variant details
- p.Thr25Ser
- Ensembl rs2150066296
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.04
- MetaLR 0.05
- MetaSVM -0.97
- CADD 0.44
- PolyPhen-2 0.01
- SIFT 0.62
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available