T25I (p.Thr25Ile) variant of TLR3 (Toll-like receptor 3)
T25I (p.Thr25Ile) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
T25I (p.Thr25Ile) variant details
- p.Thr25Ile
- Ensembl rs2099302512
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.03
- MetaLR 0.06
- MetaSVM -1.00
- CADD 4.17
- PolyPhen-2 0.01
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available