S31I (p.Ser31Ile) variant of TLR3 (Toll-like receptor 3)
S31I (p.Ser31Ile) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
S31I (p.Ser31Ile) variant details
- p.Ser31Ile
- gnomAD 4-186076711-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- REVEL 0.15
- MetaLR 0.12
- MetaSVM -0.94
- CADD 4.13
- PolyPhen-2 0.05
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available