S23F (p.Ser23Phe) variant of TLR3 (Toll-like receptor 3)
S23F (p.Ser23Phe) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S23F (p.Ser23Phe) variant details
- p.Ser23Phe
- ExAC rs769776186
- gnomAD rs769776186
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.20
- MetaLR 0.09
- MetaSVM -1.09
- CADD 11.70
- PolyPhen-2 0.42
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available