R73S (p.Arg73Ser) variant of TLR3 (Toll-like receptor 3)
R73S (p.Arg73Ser) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R73S (p.Arg73Ser) variant details
- p.Arg73Ser
- TOPMed rs2099302532
- gnomAD rs2099302532
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.23
- MetaLR 0.23
- MetaSVM -0.95
- CADD 8.66
- PolyPhen-2 0.04
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available