Q44K (p.Gln44Lys) variant of TLR3 (Toll-like receptor 3)
Q44K (p.Gln44Lys) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
Q44K (p.Gln44Lys) variant details
- p.Gln44Lys
- gnomAD 4-186076749-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.06
- CADD 12.50
- PolyPhen-2 0.03
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available