Q44H (p.Gln44His) variant of TLR3 (Toll-like receptor 3)
Q44H (p.Gln44His) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
Q44H (p.Gln44His) variant details
- p.Gln44His
- gnomAD 4-186076751-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.06
- CADD 0.50
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available