Q44E (p.Gln44Glu) variant of TLR3 (Toll-like receptor 3)
Q44E (p.Gln44Glu) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
Q44E (p.Gln44Glu) variant details
- p.Gln44Glu
- gnomAD rs1363903820
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.11
- MetaLR 0.05
- MetaSVM -1.05
- CADD 9.43
- PolyPhen-2 0.00
- SIFT 0.74
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available