N70K (p.Asn70Lys) variant of TLR3 (Toll-like receptor 3)
N70K (p.Asn70Lys) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
N70K (p.Asn70Lys) variant details
- p.Asn70Lys
- gnomAD 4-186076829-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.29
- MetaLR 0.41
- MetaSVM -0.23
- CADD 14.10
- PolyPhen-2 0.87
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available