N61K (p.Asn61Lys) variant of TLR3 (Toll-like receptor 3)
N61K (p.Asn61Lys) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
N61K (p.Asn61Lys) variant details
- p.Asn61Lys
- ExAC rs747726110
- gnomAD rs747726110
- Missense
- Variant Prioritization Score for Impact Estimate 0.548
- REVEL 0.62
- MetaLR 0.66
- MetaSVM 0.42
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available