M19V (p.Met19Val) variant of TLR3 (Toll-like receptor 3)
M19V (p.Met19Val) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
M19V (p.Met19Val) variant details
- p.Met19Val
- ExAC rs776263129
- gnomAD rs776263129
- Missense
- Variant Prioritization Score for Impact Estimate 0.092
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.00
- CADD 9.14
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 1.1e-05)
- Structural context available