M19L (p.Met19Leu) variant of TLR3 (Toll-like receptor 3)
M19L (p.Met19Leu) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
M19L (p.Met19Leu) variant details
- p.Met19Leu
- ExAC rs776263129
- gnomAD rs776263129
- Missense
- Variant Prioritization Score for Impact Estimate 0.0927
- REVEL 0.03
- MetaLR 0.04
- MetaSVM -0.98
- CADD 7.45
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available