L77V (p.Leu77Val) variant of TLR3 (Toll-like receptor 3)
L77V (p.Leu77Val) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
L77V (p.Leu77Val) variant details
- p.Leu77Val
- gnomAD 4-186076848-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.636
- REVEL 0.59
- MetaLR 0.71
- MetaSVM 0.57
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available