L66* (p.Leu66Ter) variant of TLR3 (Toll-like receptor 3)
L66* (p.Leu66Ter) in TLR3 (Toll-like receptor 3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
L66* (p.Leu66Ter) variant details
- p.Leu66Ter
- gnomAD 4-186076816-T-G
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.699
- CADD 35.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available