L5C (p.Leu5Cys) variant of TLR3 (Toll-like receptor 3)
L5C (p.Leu5Cys) in TLR3 (Toll-like receptor 3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L5C (p.Leu5Cys) variant details
- p.Leu5Cys
- gnomAD 4-186076630-CT-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.246
- CADD 23.40
- Population evidence available
- Structural context available
- Literature evidence available