L56S (p.Leu56Ser) variant of TLR3 (Toll-like receptor 3)
L56S (p.Leu56Ser) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
L56S (p.Leu56Ser) variant details
- p.Leu56Ser
- gnomAD 4-186076786-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.772
- REVEL 0.83
- MetaLR 0.82
- MetaSVM 0.95
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available