L15C (p.Leu15Cys) variant of TLR3 (Toll-like receptor 3)
L15C (p.Leu15Cys) in TLR3 (Toll-like receptor 3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
L15C (p.Leu15Cys) variant details
- p.Leu15Cys
- gnomAD 4-186076659-CT-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.465
- CADD 24.80
- Population evidence available
- Structural context available
- Literature evidence available