K27N (p.Lys27Asn) variant of TLR3 (Toll-like receptor 3)
K27N (p.Lys27Asn) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
K27N (p.Lys27Asn) variant details
- p.Lys27Asn
- TOPMed rs1188065402
- gnomAD rs1188065402
- Missense
- Variant Prioritization Score for Impact Estimate 0.0822
- REVEL 0.03
- MetaLR 0.06
- MetaSVM -1.01
- CADD 3.60
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available