I8V (p.Ile8Val) variant of TLR3 (Toll-like receptor 3)
I8V (p.Ile8Val) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
I8V (p.Ile8Val) variant details
- p.Ile8Val
- gnomAD rs1480030311
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.07
- MetaLR 0.06
- MetaSVM -0.94
- CADD 5.91
- PolyPhen-2 0.00
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available