H39R (p.His39Arg) variant of TLR3 (Toll-like receptor 3)
H39R (p.His39Arg) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
H39R (p.His39Arg) variant details
- p.His39Arg
- gnomAD rs1426637668
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.29
- MetaLR 0.06
- MetaSVM -1.07
- CADD 22.60
- PolyPhen-2 0.13
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available