H39Q (p.His39Gln) variant of TLR3 (Toll-like receptor 3)
H39Q (p.His39Gln) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
H39Q (p.His39Gln) variant details
- p.His39Gln
- gnomAD rs1168473085
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.28
- MetaLR 0.10
- MetaSVM -0.98
- CADD 8.39
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available