G18R (p.Gly18Arg) variant of TLR3 (Toll-like receptor 3)
G18R (p.Gly18Arg) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G18R (p.Gly18Arg) variant details
- p.Gly18Arg
- gnomAD rs1283113945
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.13
- MetaLR 0.05
- MetaSVM -1.06
- CADD 20.80
- PolyPhen-2 0.11
- SIFT 0.35
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available