G13V (p.Gly13Val) variant of TLR3 (Toll-like receptor 3)
G13V (p.Gly13Val) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
G13V (p.Gly13Val) variant details
- p.Gly13Val
- gnomAD 4-186076657-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.10
- MetaLR 0.06
- MetaSVM -1.03
- CADD 9.07
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available