G13S (p.Gly13Ser) variant of TLR3 (Toll-like receptor 3)
G13S (p.Gly13Ser) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G13S (p.Gly13Ser) variant details
- p.Gly13Ser
- gnomAD rs1470948740
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.07
- MetaLR 0.06
- MetaSVM -1.01
- CADD 10.60
- PolyPhen-2 0.12
- SIFT 0.43
- Most common in the Non-Finnish European population (allele frequency 9.9e-06)
- Structural context available