G13R (p.Gly13Arg) variant of TLR3 (Toll-like receptor 3)
G13R (p.Gly13Arg) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
G13R (p.Gly13Arg) variant details
- p.Gly13Arg
- gnomAD 4-186076656-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.12
- MetaLR 0.07
- MetaSVM -1.02
- CADD 12.20
- PolyPhen-2 0.01
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available