E33D (p.Glu33Asp) variant of TLR3 (Toll-like receptor 3)
E33D (p.Glu33Asp) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
E33D (p.Glu33Asp) variant details
- p.Glu33Asp
- TOPMed rs1481297372
- gnomAD rs1481297372
- Missense
- Variant Prioritization Score for Impact Estimate 0.0781
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.03
- CADD 1.95
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available