D48V (p.Asp48Val) variant of TLR3 (Toll-like receptor 3)
D48V (p.Asp48Val) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
D48V (p.Asp48Val) variant details
- p.Asp48Val
- TOPMed rs1047312739
- gnomAD rs1047312739
- Missense
- Variant Prioritization Score for Impact Estimate 0.526
- REVEL 0.53
- MetaLR 0.23
- MetaSVM -0.48
- CADD 24.60
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available