D47G (p.Asp47Gly) variant of TLR3 (Toll-like receptor 3)
D47G (p.Asp47Gly) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
D47G (p.Asp47Gly) variant details
- p.Asp47Gly
- gnomAD 4-186076759-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.06
- MetaLR 0.08
- MetaSVM -1.03
- CADD 12.40
- PolyPhen-2 0.04
- SIFT 0.11
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available