D47E (p.Asp47Glu) variant of TLR3 (Toll-like receptor 3)
D47E (p.Asp47Glu) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
D47E (p.Asp47Glu) variant details
- p.Asp47Glu
- gnomAD rs780586678
- Missense
- Variant Prioritization Score for Impact Estimate 0.0879
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.01
- CADD 1.89
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available