C7S (p.Cys7Ser) variant of TLR3 (Toll-like receptor 3)
C7S (p.Cys7Ser) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
C7S (p.Cys7Ser) variant details
- p.Cys7Ser
- gnomAD rs2099302500
- Missense
- Variant Prioritization Score for Impact Estimate 0.0948
- REVEL 0.08
- MetaLR 0.05
- MetaSVM -1.00
- CADD 0.28
- PolyPhen-2 0.01
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available