C7F (p.Cys7Phe) variant of TLR3 (Toll-like receptor 3)
C7F (p.Cys7Phe) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
C7F (p.Cys7Phe) variant details
- p.Cys7Phe
- gnomAD 4-186076639-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- REVEL 0.12
- MetaLR 0.04
- MetaSVM -0.97
- CADD 0.29
- PolyPhen-2 0.00
- SIFT 0.37
- Population evidence available
- Structural context available
- Literature evidence available