C28G (p.Cys28Gly) variant of TLR3 (Toll-like receptor 3)
C28G (p.Cys28Gly) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
C28G (p.Cys28Gly) variant details
- p.Cys28Gly
- ExAC rs766214573
- TOPMed rs766214573
- gnomAD rs766214573
- Missense
- Variant Prioritization Score for Impact Estimate 0.709
- REVEL 0.73
- MetaLR 0.77
- MetaSVM 0.70
- CADD 24.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available