A69V (p.Ala69Val) variant of TLR3 (Toll-like receptor 3)
A69V (p.Ala69Val) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
A69V (p.Ala69Val) variant details
- p.Ala69Val
- gnomAD 4-186076825-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.09
- MetaLR 0.31
- MetaSVM -0.71
- CADD 9.08
- PolyPhen-2 0.04
- SIFT 0.19
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available