A35T (p.Ala35Thr) variant of TLR3 (Toll-like receptor 3)
A35T (p.Ala35Thr) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
A35T (p.Ala35Thr) variant details
- p.Ala35Thr
- gnomAD 4-186076722-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.34
- MetaLR 0.16
- MetaSVM -0.82
- CADD 24.90
- PolyPhen-2 0.73
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available