A35S (p.Ala35Ser) variant of TLR3 (Toll-like receptor 3)
A35S (p.Ala35Ser) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
A35S (p.Ala35Ser) variant details
- p.Ala35Ser
- gnomAD 4-186076722-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- REVEL 0.29
- MetaLR 0.20
- MetaSVM -0.76
- CADD 24.30
- PolyPhen-2 0.73
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available