A22V (p.Ala22Val) variant of TLR3 (Toll-like receptor 3)
A22V (p.Ala22Val) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
A22V (p.Ala22Val) variant details
- p.Ala22Val
- gnomAD 4-186076684-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0787
- REVEL 0.04
- MetaLR 0.05
- MetaSVM -1.03
- CADD 0.96
- PolyPhen-2 0.00
- SIFT 0.74
- Population evidence available
- Structural context available
- Literature evidence available