S81L (p.Ser81Leu) variant of THRB (Thyroid hormone receptor beta)
S81L (p.Ser81Leu) in THRB (Thyroid hormone receptor beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
S81L (p.Ser81Leu) variant details
- p.Ser81Leu
- TOPMed rs1301951155
- Missense
- Variant Prioritization Score for Impact Estimate 0.603
- CADD 19.90
- PolyPhen-2 0.00
- SIFT 0.23
- Population evidence available
- Structural context available