S66A (p.Ser66Ala) variant of THRB (Thyroid hormone receptor beta)
S66A (p.Ser66Ala) in THRB (Thyroid hormone receptor beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
S66A (p.Ser66Ala) variant details
- p.Ser66Ala
- ExAC rs750270307
- TOPMed rs750270307
- gnomAD rs750270307
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- CADD 21.70
- PolyPhen-2 0.01
- SIFT 0.23
- Population evidence available
- Structural context available