R46G (p.Arg46Gly) variant of THRB (Thyroid hormone receptor beta)
R46G (p.Arg46Gly) in THRB (Thyroid hormone receptor beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R46G (p.Arg46Gly) variant details
- p.Arg46Gly
- ExAC rs754933969
- gnomAD rs754933969
- Missense
- Variant Prioritization Score for Impact Estimate 0.396
- CADD 18.90
- PolyPhen-2 0.00
- SIFT 0.13
- Population evidence available
- Structural context available