L58F (p.Leu58Phe) variant of THRB (Thyroid hormone receptor beta)
L58F (p.Leu58Phe) in THRB (Thyroid hormone receptor beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
L58F (p.Leu58Phe) variant details
- p.Leu58Phe
- cosmic curated COSV62841
- Missense
- Variant Prioritization Score for Impact Estimate 0.721
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.02
- Population evidence available
- Structural context available