L106P (p.Leu106Pro) variant of THRB (Thyroid hormone receptor beta)
L106P (p.Leu106Pro) in THRB (Thyroid hormone receptor beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
L106P (p.Leu106Pro) variant details
- p.Leu106Pro
- TOPMed rs1254993640
- gnomAD rs1254993640
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- CADD 23.00
- PolyPhen-2 0.05
- SIFT 0.12
- Population evidence available
- Structural context available