I59L (p.Ile59Leu) variant of THRB (Thyroid hormone receptor beta)
I59L (p.Ile59Leu) in THRB (Thyroid hormone receptor beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
I59L (p.Ile59Leu) variant details
- p.Ile59Leu
- cosmic curated COSV62836
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- CADD 16.20
- PolyPhen-2 0.00
- SIFT 0.96
- Population evidence available
- Structural context available