G95E (p.Gly95Glu) variant of THRB (Thyroid hormone receptor beta)
G95E (p.Gly95Glu) in THRB (Thyroid hormone receptor beta) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
G95E (p.Gly95Glu) variant details
- p.Gly95Glu
- cosmic curated COSV10880
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.812
- CADD 28.90
- PolyPhen-2 0.93
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available