F68L (p.Phe68Leu) variant of THRB (Thyroid hormone receptor beta)
F68L (p.Phe68Leu) in THRB (Thyroid hormone receptor beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
F68L (p.Phe68Leu) variant details
- p.Phe68Leu
- gnomAD rs1369173973
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- CADD 18.70
- PolyPhen-2 0.01
- SIFT 0.17
- Population evidence available
- Structural context available