D26N (p.Asp26Asn) variant of THRB (Thyroid hormone receptor beta)
D26N (p.Asp26Asn) in THRB (Thyroid hormone receptor beta) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
D26N (p.Asp26Asn) variant details
- p.Asp26Asn
- rs776036533
- NCI-TCGA Cosmic COSV6283
- cosmic curated COSV62833
- ExAC rs776036533
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- CADD 18.50
- PolyPhen-2 0.00
- SIFT 0.51
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available