C20Y (p.Cys20Tyr) variant of THRB (Thyroid hormone receptor beta)
C20Y (p.Cys20Tyr) in THRB (Thyroid hormone receptor beta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
C20Y (p.Cys20Tyr) variant details
- p.Cys20Tyr
- ExAC rs765488277
- gnomAD rs765488277
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- CADD 19.20
- PolyPhen-2 0.01
- SIFT 0.11
- Population evidence available
- Structural context available