A26G (p.Ala26Gly) variant of TGFBR1 (TGF-beta receptor type-1)
A26G (p.Ala26Gly) in TGFBR1 (TGF-beta receptor type-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
A26G (p.Ala26Gly) variant details
- p.Ala26Gly
- gnomAD 9-99105282-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.15
- CADD 14.70
- PolyPhen-2 0.01
- SIFT 0.34
- Most common in the African/African-American population (allele frequency 6.1e-05)
- Structural context available
- Literature evidence available