T74A (p.Thr74Ala) variant of TGFB2 (P61812)
T74A (p.Thr74Ala) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
T74A (p.Thr74Ala) variant details
- p.Thr74Ala
- gnomAD 1-218346921-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.679
- REVEL 0.68
- CADD 31.00
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available