S73I (p.Ser73Ile) variant of TGFB2 (P61812)
S73I (p.Ser73Ile) in TGFB2 (P61812) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
S73I (p.Ser73Ile) variant details
- p.Ser73Ile
- gnomAD 1-218346919-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.766
- REVEL 0.72
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available